“One-Pot” Multicomponent Approach to Indolizines and Pyrido[1,2-a]indoles
Organic Letters2011Vol. 13(10), pp. 2792–2794
Citations Over TimeTop 10% of 2011 papers
Abstract
A new synthetic protocol for efficient and regiospecifc assembly of indolizines and pyrido[1,2-a]indoles by coupling of substituted methyl bromides and alkynes with corresponding pyrrole-2-carboxaldehyde and 1H-indole-2-carboxaldehyde has been developed. Additionally, a possible mechanism for the reaction is proposed.
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