Pyrophosphate-Selective Fluorescent Chemosensor Based on 1,8-Naphthalimide–DPA–Zn(II) Complex and Its Application for Cell Imaging
Organic Letters2011Vol. 13(19), pp. 5294–5297
Citations Over TimeTop 10% of 2011 papers
Jun Feng Zhang, Sooyeon Kim, Ji Hae Han, Seung-Jea Lee, Tuhin Pradhan, Qian Cao, Suk Joong Lee, Chulhun Kang, Jong Seung Kim
Abstract
A new zinc(II) complex with a two-dipicolylamine-substituted 1,8-naphthalimide for recognition of pyrophosphate with ratiometrical fluorescence changes in aqueous solution has been synthesized and characterized. Its biological application to monitor the intracellular pyrophosphate (PPi) was successfully demonstrated by the observation that the fluorescence of 1 was enhanced by the presence of the Zn(2+) ion and was quenched by addition of PPi.
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