Asymmetric Hydrogenation of 2- and 2,3-Substituted Quinoxalines with Chiral Cationic Ruthenium Diamine Catalysts
Organic Letters2011Vol. 13(24), pp. 6568–6571
Citations Over TimeTop 10% of 2011 papers
Abstract
The enantioselective hydrogenation of 2-alkyl- and 2-aryl-subsituted quinoxalines and 2,3-disubstituted quinoxalines was developed by using the cationic Ru(η(6)-cymene)(monosulfonylated diamine)(BArF) system in high yields with up to 99% ee. The counteranion was found to be critically important for the high enantioselectivity and/or diastereoselectivity.
Related Papers
- → [(Bisphosphine) Ru(II) Diamine] Complexes in Asymmetric Hydrogenation: Expanding the Scope of the Diamine Ligand(2007)114 cited
- → Asymmetric Hydrogenation of Isobutyrophenone Using a [(Diphosphine) RuCl2 (1,4-Diamine)] Catalyst(2005)42 cited
- → Enantioselective Hydrogenation of Diarylmethanimines for Synthesis of Chiral Diarylmethylamines(2016)41 cited
- → Synthesis and application in enantioselective hydrogenation of a rhodium complex of an asymmetric water-soluble diphosphine PGE-17-DIOP(1984)48 cited
- → Reduction of Functionalized Alkenes(2008)5 cited