Reaction Based Fluorescent Probes for Hydrogen Sulfide
Organic Letters2012Vol. 14(8), pp. 2184–2187
Citations Over TimeTop 1% of 2012 papers
Abstract
A reaction based fluorescence turn-on strategy for hydrogen sulfide (H(2)S) was developed. This strategy was based on a H(2)S-specific Michael addition-cyclization sequence. Other biological thiols such as cysteine and glutathione did not pursue the reaction and therefore did not turn on the fluorescence/consume the substrates. The probes showed good selectivity and sensitivity for hydrogen sulfide.
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