One-Pot Multicomponent Cascade Reaction of N,S-Ketene Acetal: Solvent-Free Synthesis of Imidazo[1,2-a]thiochromeno[3,2-e]pyridines
Organic Letters2012Vol. 14(13), pp. 3470–3473
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Abstract
Unprecedented imidazo[1,2-a]thiochromeno[3,2-e]pyridines have been synthesized via a three-component cascade reaction under solvent-free conditions. This one-pot transformation involving multiple steps and not requiring the use of transition metal catalysts constructs three new C-C bonds, two C-N bonds, one C-S bond, and three new rings with all reactants efficiently utilized.
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