Isocyanide-Based Multicomponent Reactions: Catalyst-Free Stereoselective Construction of Polycyclic Spiroindolines
Organic Letters2013Vol. 15(8), pp. 1954–1957
Citations Over TimeTop 10% of 2013 papers
Abstract
A novel catalyst-free one-pot tandem reaction for the stereoselective construction of polycyclic spiroindolines was developed. This method offers a straightforward access to structurally diverse polycyclic spiroindoline derivatives in high yields (up to 90%) with excellent levels of diastereoselectivity.
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