Efficient Access to 1,4-Benzothiazine: Palladium-Catalyzed Double C–S Bond Formation Using Na2S2O3 as Sulfurating Reagent
Organic Letters2013Vol. 15(11), pp. 2594–2597
Citations Over TimeTop 1% of 2013 papers
Abstract
A novel Pd-catalyzed double C-S bond formation coupling reaction has been developed. This protocol, in which Na2S2O3 was used as sulfurating reagent in metal-catalyzed reactions, provides an efficient method for the synthesis of substituted 1,4-benzothiazine derivates, which are structural elements of numerous bioactivity molecules rendering this protocol attractive to both synthetic and medicinal chemistry.
Related Papers
- → A novel photoisomerzation of 1,2‐benzothiazine 1,1‐dioxides to 1,3‐benzothiazine 1,1‐dioxides(2007)8 cited
- → Azomethyne derivatives of 1,3-benzothiazine 1,1-dioxide(2010)1 cited
- → New 1,4-benzothiazine fused heterocycles-V : Synthesis of 9H-thieno[ 3,2-b]benzothiazine and 4H-thiazolo[2,3-b][1,4] benzothiazine derivatives(2001)9 cited
- → ChemInform Abstract: SYNTHESIS OF 2H‐ AND 4H‐1,3‐BENZOTHIAZINE DERIVATIVES. STUDIES OF THE 1,3‐BENZOTHIAZINE RING CLOSURE REACTION OF N‐(3,4‐DIALKOXYPHENYLTHIOMETHYL) ACID AMIDES(1978)
- → ChemInform Abstract: 2,1‐Benzothiazine 2,2‐Dioxides. Part 5. Hydrolysis of Alkyl 1‐R‐4‐Hydroxy‐2,2‐dioxo‐1H‐2λ 6,1‐benzothiazine‐3‐carboxylates.(2015)