Palladium-Catalyzed Olefination and Arylation of 2-Substituted 1,2,3-Triazole N-Oxides
Organic Letters2013Vol. 15(10), pp. 2342–2345
Citations Over TimeTop 10% of 2013 papers
Abstract
Two highly efficient protocols for the regioselective synthesis of 2-substituted 4-alkenyl- and 4-aryl-1,2,3-triazoles by the palladium-catalyzed C-H functionalization of 1,2,3-triazole N-oxides are reported. A possible pathway of direct alkenylation with 1-octene and vinyl acetate is discussed.
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