Construction of 2-Substituted-3-Functionalized Benzofurans via Intramolecular Heck Coupling: Application to Enantioselective Total Synthesis of Daphnodorin B
Organic Letters2013Vol. 15(18), pp. 4742–4745
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Yuan Hu, Kaijian Bi, Bo Li, Rongcai Yue, Ji Ye, Yun‐Heng Shen, Lei Shan, Hui‐Zi Jin, Qingyan Sun, Weidong Zhang
Abstract
A novel approach was developed for the synthesis of 2-substituted-3-functionalized benzofurans, using an intramolecular Heck reaction which was further applied in the first enantioselective total synthesis of Daphnodorin B.
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