I2/TBHP-Catalyzed Chemoselective Amination of Indoles
Organic Letters2013Vol. 15(20), pp. 5226–5229
Citations Over TimeTop 10% of 2013 papers
Abstract
A novel I2/TBHP-mediated direct oxidative diamination reaction of indoles with anilines was developed. The reaction proceeded smoothly under aqueous and open air reaction conditions. This protocol provides a practical synthetic method for the synthesis of Tryptanthrin and the construction of N-C3 linked pyrrolidinoindolines which is the core structure of Psychotrimine.
Related Papers
- → A review on the effect of amination pretreatment for the selective separation of CO2(2015)49 cited
- → Advances in the Direct Amination of Azole C-H Bonds(2011)26 cited
- → Recent Progress in Amination Enabled by Transition-Metal-Free C(sp2)–O/C(sp2)–S Bond Cleavage Strategy(2021)3 cited
- → Catalytic CH Amination with Nitrenes(2007)5 cited
- → ChemInform Abstract: Recent Advances in Transition Metal‐Catalyzed sp3 C—H Amination Adjacent to Double Bonds and Carbonyl Groups(2012)