Metal-Free, Acid-Promoted Synthesis of Imidazole Derivatives via a Multicomponent Reaction
Organic Letters2013Vol. 15(24), pp. 6116–6119
Citations Over TimeTop 10% of 2013 papers
Abstract
An expedient and metal-free synthetic route has been developed for the construction of tri- and tetrasubstituted imidazole derivatives via acid promoted multicomponent reaction methodology. The reaction proceeded smoothly with a range of functionalities to produce the imidazole scaffolds in good to excellent yields.
Related Papers
- → Stepwise Fusion of Porphyrin β,β′-Pyrrolic Positions to Imidazole Rings(2011)37 cited
- → Synthesis of Bi‐ and tridentate imidazole ligands(1977)19 cited
- → 4-Phenyl-1H-imidazole (a low-temperature redetermination), 1-benzyl-1H-imidazole and 1-mesityl-1H-imidazole(2004)8 cited
- NMR Studies on Interactions between Diperoxovanadate and Imidazole-like Ligands(2007)
- → ChemInform Abstract: REACTIONS OF ALKOXYCARBONYLCARBENOIDS WITH IMIDAZOLE; AN IMPROVED PREPARATION OF ETHYL IMIDAZOLE‐1‐YLACETATE AND THE FIRST SYNTHESIS OF DIETHYL IMIDAZOLE‐1‐YLMALONATE(1981)