Cobalt-Catalyzed Cyclization of Carbon Monoxide, Imine, and Epoxide
Organic Letters2014Vol. 16(8), pp. 2130–2133
Citations Over TimeTop 17% of 2014 papers
Abstract
Cobalt-catalyzed cyclization of CO, imine, and epoxide has been developed. A convenient catalyst system composed of Co2(CO)8 and LiCl is identified, and the substrate scope has been explored. The reaction provides an efficient method for the synthesis of substituted 1,3-oxazinan-4-ones.
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