Palladium-Catalyzed Formylation of Aryl Halides with tert-Butyl Isocyanide
Organic Letters2014Vol. 16(13), pp. 3492–3495
Citations Over TimeTop 10% of 2014 papers
Abstract
A novel palladium-catalyzed formylation of aryl halides with isocyanide in the presence of Et3SiH has been demonstrated, which provides a strategy toward important aldehydes with moderate to excellent yield. The advantage of this reaction includes milder conditions, convenient operation, lower toxicity, and wide functional group tolerance.
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