Copper-Catalyzed Intramolecular Oxytrifluoromethylthiolation of Unactivated Alkenes
Organic Letters2014Vol. 16(20), pp. 5390–5393
Citations Over TimeTop 10% of 2014 papers
Abstract
A mild, versatile, and convenient method for efficient intramolecular oxytrifluoromethylthiolation of unactivated alkenes catalyzed by Cu(OAc)2 has been developed. The reactions were carried out under aerobic conditions and formed a variety of isoxazolines bearing a -SCF3 substituent.
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