Total Synthesis of Iejimalide B. An Application of the Shiina Macrolactonization
Organic Letters2007Vol. 9(22), pp. 4619–4622
Citations Over TimeTop 14% of 2007 papers
Abstract
The potent anticancer compound iejimalide B (1) was prepared by a total synthesis through a strategy that features Julia olefinations, Wittig olefinations, a Carreira enantioselective alkynylation, a Heck reaction, a Marshall propargylation reaction, a Stille coupling, and a Shiina macrolactonization.
Related Papers
- → One-pot synthesis of stilbenes by dehydrohalogenation–Heck olefination and multicomponent Wittig–Heck reaction(2010)39 cited
- → Novel Synthesis of Oxathiocine Derivatives by Wittig Olefination and Intramolecular Heck Reaction via an 8-endo-trig Cyclization(2008)19 cited
- → Alternation of Chemoselective Control in Stille–Heck and Heck–Stille Reaction Sequences(2009)12 cited
- → Studies for the Total Synthesis of Amphidinolide P(2013)15 cited
- → ChemInform Abstract: Synthesis of 2‐Naphthols via Carbonylative Stille Coupling Reaction of 2‐Bromobenzyl Bromides with Tributylallylstannane Followed by the Heck Reaction.(2012)