Synthesis of Modified DNA by PCR with Alkyne-Bearing Purines Followed by a Click Reaction
Organic Letters2007Vol. 10(2), pp. 249–251
Citations Over TimeTop 10% of 2007 papers
Abstract
Alkyne-bearing deazapurine triphosphates were prepared and successfully incorporated into DNA using the polymerase chain reaction (PCR). The obtained alkyne-labeled DNA was successfully used in a click reaction with galactose azide.
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