Copper-Catalyzed Coupling of Hydroxylamines with Aryl Iodides
Organic Letters2008Vol. 10(5), pp. 797–800
Citations Over TimeTop 10% of 2008 papers
Abstract
An efficient method for the copper-catalyzed N-arylation of hydroxylamines with aryl iodides is described. A variety of N- and O-functionalized hydroxylamines were transformed in good to excellent yield with a broad range of aryl coupling partners. Methods for the selective deprotection of either the N- or O-substituents for further functionalization are also described.
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