Ainsliatrimers A and B, the First Two Guaianolide Trimers from Ainsliaea fulvioides
Organic Letters2008Vol. 10(24), pp. 5517–5520
Citations Over TimeTop 18% of 2008 papers
Yan Wang, Yun‐Heng Shen, Hui‐Zi Jin, Jianjun Fu, Xiaojia Hu, Jiang‐Jiang Qin, Jianhua Liu, Ming Chen, Shikai Yan, Weidong Zhang
Abstract
Ainsliatrimers A (1) and B (2), the first two guaianolide-type sesquiterpene lactone trimers, together with one new structurally related sesquiterpene dimer ainsliadimer B (3), were isolated from the aerial part of Ainsliaea fulvioides. Their structures were elucidated by spectroscopic techniques, including X-ray crystal diffraction. Both 1 and 2 showed potent cytotoxicites against LOVO and CEM cell lines.
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