An Efficient One-Pot Copper-Catalyzed Approach to Isoquinolin-1(2H)-one Derivatives
Organic Letters2009Vol. 11(11), pp. 2469–2472
Citations Over TimeTop 10% of 2009 papers
Abstract
A simple and efficient copper-catalyzed method for synthesis of 3,4-disubstituted isoquinolin-1(2H)-one derivatives via cascade reactions of substituted 2-halobenzamides with beta-keto esters under mild conditions has been developed, and the method has economical and practical advantages.
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