C−H Bond Functionalization via Hydride Transfer: Synthesis of Dihydrobenzopyrans from ortho-Vinylaryl Akyl Ethers
Organic Letters2009Vol. 11(14), pp. 2972–2975
Citations Over TimeTop 10% of 2009 papers
Abstract
The hydride transfer initiated cyclization ("HT-cyclization") of aryl alkyl ethers, which leads to direct coupling of sp(3) C-H bonds and activated alkenes, is reported. Readily available salicylaldehyde derived ethers are converted in one step to dihydrobenzopyrans, an important class of heteroarenes frequently found in biologically active compounds. This process has not been previously reported, in contrast to known HT-cyclizations of the corresponding tert-amines ("tert-amino effect" reactions).
Related Papers
- → Maskless functionalization of a carbon nanotube dot array biosensor using an ultrafine atmospheric pressure plasma jet(2015)47 cited
- → Surface functionalization of microporous carbon fibers by vapor phase methods for CO2 capture(2023)3 cited
- → Selective external surface functionalization of large-pore silica materials capable of protein loading(2016)24 cited
- → Thermal Functionalization of GaN Surfaces with 1-Alkenes(2013)13 cited
- → ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ(2024)