Stereocontrolled Synthesis of Oxaspirobicycles via Prins-Pinacol Annulation
Organic Letters2009Vol. 11(17), pp. 3834–3837
Citations Over TimeTop 13% of 2009 papers
Satish N. Chavre, Punna Reddy Ullapu, Sun‐Joon Min, Jae Kyun Lee, Ae Nim Pae, Youseung Kim, Yong Seo Cho
Abstract
We have developed the stereoselective synthesis of 2-oxaspiro[m,n]alkane derivatives using the Prins-pinacol annulation of alkene diols with a wide range of aliphatic or aromatic aldehydes and ketones. This approach was further applied for the synthesis of oxatricyclic ring system.
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