An Asymmetric Hetero-Claisen Approach to 3-Alkyl-3-aryloxindoles
Organic Letters2009Vol. 11(17), pp. 3858–3861
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Abstract
The reaction of a chiral N-phenylnitrone derived from Garner's aldehyde with alkylarylketenes generates 3-alkyl-3-aryloxindoles directly in excellent yields and with good to excellent levels of enantioselectivity (up to 90% ee).
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