Domino Ring-Opening/Carboxamidation Reactions of N-Tosyl Aziridines and 2-Halophenols/Pyridinol: Efficient Synthesis of 1,4-Benzo- and Pyrido-oxazepinones
Organic Letters2009Vol. 12(1), pp. 192–195
Citations Over TimeTop 14% of 2009 papers
Abstract
A domino process is described for the synthesis of 1,4-benzo- and pyrido-oxazepinones by one-pot sequential ring-opening/carboxamidation reactions of various N-tosylaziridines with a range of 2-halophenols/pyridinol under phase-transfer catalysis.
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