Anti-Markovnikov Hydroarylation of Unactivated Olefins Catalyzed by a Bis-tropolonato Iridium(III) Organometallic Complex

Citations Over TimeTop 10% of 2005 papers

Abstract

Recently, we reported the first catalytic, intermolecular, anti-Markovnikov hydroarylation of unactivated olefins by a homogeneous, bis-chelating, O-donor Ir(III) complex, (acac-O,O)2Ir(R)(L), based on the simplest β-diketonate acetylacetonate (acac-O,O). With the ultimate objective of designing more active catalysts for this potentially useful reaction on the basis of structure function studies, we synthesized the related O-donor, bis-tropolonato Ir(III) organometallic analogues. Herein, we report that the new O-donor complex, (trop-O,O)2Ir(Ph)(Py), is an active catalyst for the anti-Markovnikov hydroarylation of unactivated olefins and that theoretical calculations are consistent with catalysis proceeding via arene CH activation and olefin insertion.

Related Papers

• → Silver-Mediated anti-Markovnikov and Markovnikov-Selective Hydrotrifluoromethylthiolation of Terminal Alkynes(2016)61 cited
• → Cobalt-catalyzed Divergent Markovnikov and Anti-Markovnikov Hydroamination(2021)37 cited
• → Enzymatic Anti-Markovnikov Oxidations of Styrenes(2017)
• → ChemInform Abstract: Silver‐Mediated anti‐Markovnikov and Markovnikov‐Selective Hydrotrifluoromethylthiolation of Terminal Alkynes.(2016)