A Convenient Method of Synthesis of Unsymmetrical Urea Derivatives
Organic Process Research & Development2002Vol. 6(6), pp. 759–761
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Abstract
A method for the preparation of unsymmetrical urea derivatives that may contain functional groups such as hydroxyl, amine, amide, and carboxyl is described. The method consists of a one-pot modified Curtius rearrangement starting with appropriate aromatic acid chloride and carried out in a nonaqueous system
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