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Process Development of Selectively Benzoylated and Fluorinated Glycosyl Donors
Organic Process Research & Development2010Vol. 14(3), pp. 623–631
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Franz J. Weiberth, Harpal S. Gill, Ying Jiang, George E. Lee, Philippe Lienard, Clive Pemberton, Matthew R. Powers, Witold Subotkowski, W. TOMASIK, Benoit Vanasse, Yong Yu
Abstract
Route selection, process development and large-scale preparation of selectively benzoylated and fluorinated d-glucopyranoses, required as glycosyl donors for the synthesis of the SGLT inhibitor SAR7226, are discussed.
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