Design of Experiments (DoE) and Process Optimization. A Review of Recent Publications
Organic Process Research & Development2014Vol. 19(11), pp. 1605–1633
Citations Over TimeTop 10% of 2014 papers
Abstract
Statistical design of experiments (DoE) is a powerful tool for optimizing processes, and it has been used in many stages of API development. This review summarizes selected publications from Organic Process Research & Development using DoE to show how processes can be optimized efficiently and how DoE findings may be applied to scale-up.
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