DTASelect and Contrast: Tools for Assembling and Comparing Protein Identifications from Shotgun Proteomics
Journal of Proteome Research2002Vol. 1(1), pp. 21–26
Citations Over TimeTop 1% of 2002 papers
Abstract
The components of complex peptide mixtures can be separated by liquid chromatography, fragmented by tandem mass spectrometry, and identified by the SEQUEST algorithm. Inferring a mixture's source proteins requires that the identified peptides be reassociated. This process becomes more challenging as the number of peptides increases. DTASelect, a new software package, assembles SEQUEST identifications and highlights the most significant matches. The accompanying Contrast tool compares DTASelect results from multiple experiments. The two programs improve the speed and precision of proteomic data analysis.
Related Papers
- → Advances in chromatographic techniques and methods in shotgun proteome analysis(2006)58 cited
- → Analysis of Rice Proteins Using SDS-PAGE Shotgun Proteomics(2013)13 cited
- → Shotgun Approaches for Venom Analysis(2014)2 cited
- → Protein Analysis by Shotgun Proteomics(2019)17 cited
- Evolution and Application of Shotgun Strategy for Proteome Study(2006)