Matrix Implanted Laser Desorption Ionization (MILDI) Combined with Ion Mobility-Mass Spectrometry for Bio-Surface Analysis
Journal of Proteome Research2005Vol. 4(2), pp. 540–545
Citations Over TimeTop 10% of 2005 papers
A. Tempez, Michael Ugarov, Thomas F. Egan, J. Schultz, А. В. Новиков, S. Della‐Negra, Y. LeBeyec, M. Pautrat, Martine Caroff, Vincent S. Smentkowski, H-Y. J. Wang, Shelley N. Jackson, Amina S. Woods
Abstract
The implantation of low velocity massive gold cluster ions allows homogeneous incorporation of a metallic matrix into the near-surface region of rat brain tissues. Subsequent analysis by laser desorption ionization mass spectrometry yields spectra exhibiting molecular ion peaks in the mass range up to 35 kDa similar to those observed by matrix-assisted LDI. Matrix-implanted LDI when combined with ion-mobility preseparation promises to be a useful technique for molecular imaging of biotissues with a laser microprobe.
Related Papers
- → Dual Desorption Electrospray Ionization−Laser Desorption Ionization Mass Spectrometry on a Common Nanoporous Alumina Platform for Enhanced Shotgun Proteomic Analysis(2008)18 cited
- → Recent Progress of Two-step Laser Desorption/Laser Ionization Mass Spectrometry and its Application(2011)5 cited
- → Laser desorption multiphoton ionization mass spectrometry(1991)5 cited
- → Laser Desorption and Laser Post-Ionization Time of Flight Mass Spectrometry(1991)1 cited