Relation of depot-specific adipose inflammation to insulin resistance in human obesity
Nutrition and Diabetes2012Vol. 2(3), pp. e30–e30
Citations Over TimeTop 10% of 2012 papers
Sherman Bigornia, Melissa G. Farb, Melanie M. Mott, Donald T. Hess, Brian Carmine, Antonino J. Fiscale, Lija Joseph, Caroline M. Apovian, Noyan Gokce
Abstract
In severely obese participants, systemic insulin resistance is linked to adipose inflammation in both subcutaneous and visceral depots. The findings suggest that examination of subcutaneous regions that are more easily accessible by transcutaneous biopsy may prove useful in clinical studies designed to investigate adipose phenotypes in relation to human disease.
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