Eicosapentaenoic Acid Induces mRNA Expression of Peroxisome Proliferator‐Activated Receptor γ
Obesity Research2002Vol. 10(6), pp. 518–525
Citations Over TimeTop 11% of 2002 papers
C. Chambrier, Jean‐Philippe Bastard, Jennifer Rieusset, Emmanuel Chevillotte, Dominique Bonnefont‐Rousselot, Patrice Thérond, Bernard Hainque, Jean‐Paul Riou, Martine Laville, Hubert Vidal
Abstract
Our results demonstrate that adipose tissue PPARgamma1 mRNA concentration is positively regulated by EPA, suggesting that the composition of dietary lipids may affect PPARgamma gene expression in vivo in humans. These data also suggest that an induction of the expression of this nuclear receptor isoform might be involved in the mechanism of action of EPA and in some of its beneficial effects.
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