Effect of Lifestyle Modification on Adipokine Levels in Obese Subjects with Insulin Resistance
Obesity Research2003Vol. 11(9), pp. 1048–1054
Citations Over TimeTop 1% of 2003 papers
Lais U. Monzillo, Osama Hamdy, Edward S. Horton, Sarah Ledbury, Cathy Mullooly, Catherine Jarema, Satoko Porter, Kerry Ovalle, Amr Moussa, Christos S. Mantzoros
Abstract
Weight reduction in obese individuals with insulin resistance was associated with a significant decrease in leptin and IL-6 and a tendency toward a decrease in circulating TNF-alpha, whereas adiponectin was increased only in diabetic subjects. Further studies are needed to elucidate the relationship between changes of adipokines and the health benefits of weight loss.
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