Low-intensity pulsed ultrasound treatment improved the rate of autograft peripheral nerve regeneration in rat
Citations Over TimeTop 10% of 2016 papers
Abstract
Low intensity pulsed ultrasound (LIPUS) has been widely used in clinic for the treatment of repairing pseudarthrosis, bone fractures and of healing in various soft tissues. Some reports indicated that LIPUS accelerated peripheral nerve regeneration including Schwann cells (SCs) and injured nerves. But little is known about its appropriate intensities on autograft nerves. This study was to investigate which intensity of LIPUS improved the regeneration of gold standard postsurgical nerves in experimental rat model. Sprague-Dawley rats were made into 10 mm right side sciatic nerve reversed autologous nerve transplantation and randomly treated with 250 mW/cm(2), 500 mW/cm(2) or 750 mW/cm(2) LIPUS for 2-12 weeks after operation. Functional and pathological results showed that LIPUS of 250 mW/cm(2) significantly induced faster rate of axonal regeneration. This suggested that autograft nerve regeneration was improved.
Related Papers
- → Gellan Gum-based luminal fillers for peripheral nerve regeneration: anin vivostudy in the rat sciatic nerve repair model(2018)39 cited
- → Dynamic change of numbl expression after sciatic nerve crush and its role in Schwann cell differentiation(2012)7 cited
- → Post-Natal Replication of Schwann Cell in Chicken Sciatic Nerve(1972)1 cited
- The methodological study of Schwann cell culture from sciatic nerve of adult SD rat(2002)
- [Regeneration of the sciatic nerve after plastic repair of a defect in it using a cryopreserved allograft].(1987)