Total synthesis of 26-hydroxyepothilone B and related analogues
Chemical Communications1997Iss. 24, pp. 2343–2344
Citations Over TimeTop 17% of 1997 papers
Abstract
A series of 26-substituted epothilones B (3, 22, 23a–n and 24a–h,j–l,o) have been constructed by total synthesis involving a selective Wittig olefination, an aldol reaction and a macrolactonization as key steps.
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