Atropisomeric amides: stereoselective enolate chemistry and enantioselective synthesis via a new SmI2-mediated reduction
Journal of the Chemical Society Perkin Transactions 11999Iss. 10, pp. 1295–1304
Citations Over TimeTop 10% of 1999 papers
Abstract
The use of certain types of atropisomeric amides, incorporating an N-MEM-ortho-tert-butylaniline group, for stereoselective reactions, has been explored. Enolate reactions of these systems are highly diastereocontrolled, and enantiomerically enriched starting materials can be obtained, starting from lactic acid, via a new SmI2 mediated reduction process.
Related Papers
- → Recent developments in enantioselective iron-catalyzed transformations(2019)58 cited
- → Alternative Synthetic Strategies for Enantioselective Construction of Halogenated Chiral Carbon Centers(2010)37 cited
- → Methods of Asymmetric Synthesis—Enantioselective Catalytic Hydrogenation(1971)142 cited
- → Chiral B(III) Lewis Acids(2000)19 cited
- → Unactivated Alkenes(2009)3 cited