Bis-aminals: efficient tools for bis-macrocycle synthesis
New Journal of Chemistry2001Vol. 25(9), pp. 1168–1174
Citations Over TimeTop 10% of 2001 papers
Michel Le Baccon, Françoise Chuburu, Loı̈c Toupet, Henri Handel, Mathieu Soibinet, Isabelle Déchamps‐Olivier, Jean‐Pierre Barbier, Michel Aplincourt
Abstract
Tetraazamacrocyclic bis-aminals prove to be excellent tools for the synthesis of symmetrical, dissymmetrical or functionalized bis-tetraazamacrocycles. The key feature of the process is the separation of insoluble mono- or bis-quaternary ammonium salts from solution during the course of the alkylation reaction.
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