New and easy route to primary cyclopropylamines from nitriles
Chemical Communications2001Iss. 18, pp. 1792–1793
Citations Over TimeTop 10% of 2001 papers
Abstract
Starting from readily available substrates, we have developed a new synthesis of primary cyclopropylamines. The reaction involves a cooperative Ti(II)- and Lewis acid-mediated coupling of alkanenitriles with Grignard reagents.
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