Thioglycosynthases: double mutant glycosidases that serve as scaffolds for thioglycoside synthesis
Chemical Communications2004Iss. 3, pp. 274–275
Citations Over TimeTop 10% of 2004 papers
Michael Jahn, Hongming Chen, Johannes Müllegger, Jennifer Marles, R. Antony J. Warren, Stephen G. Withers
Abstract
A double mutant, retaining glycosidase that lacks both the catalytic nucleophile and the catalytic acid/base residues efficiently catalyzes thioglycoside formation from a glycosyl fluoride donor and thiosugar acceptors.
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