Encapsulated photosensitive drugs by biodegradable microcapsules to incapacitate cancer cells
Journal of Materials Chemistry2007Vol. 17(38), pp. 4018–4018
Citations Over TimeTop 10% of 2007 papers
Abstract
A hydrophobic photodynamic therapy drug, hypocrellin B (HB), was accumulated in water-solubilized natural polyelectrolyte microcapsules. The HB can be effectively encapsulated, delivered and subsequently taken up by cancer cells. These intracellular HB-loaded microcapsules show biocompatibility under darkness and high cytotoxicity after irradiation which provides the possibility of controlled delivery and release of drugs.
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