Acid cleavable PEG-lipids for applications in a ternary gene delivery vector
Molecular BioSystems2008Vol. 4(6), pp. 532–541
Citations Over TimeTop 20% of 2008 papers
Abstract
A novel class of pH-sensitive PEG lipids bearing acid-cleavable acetal linkages and short PEG chains have been synthesised and used in ternary vector formulations. The cleavage pH was influenced by structural components including the terminal PEG moiety and spacer length.
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