On-site manipulation of single chromosomal DNA molecules by using optically driven microstructures
Lab on a Chip2008Vol. 8(8), pp. 1280–1280
Citations Over Time
Abstract
We report a novel method for manipulation of single giant DNA molecules under a video microscope. Using optically driven microstructures, we manipulated chromosomal DNA of length in the order of millimetres, extended by electroosmotic flow without DNA breakage in aqueous solution: we picked up DNA, using microfabricated hooks and wound it around microfabricated bobbins.
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