Glycoarrays—tools for determining protein–carbohydrate interactions and glycoenzyme specificity
Chemical Communications2008Iss. 37, pp. 4400–4400
Citations Over TimeTop 10% of 2008 papers
Abstract
Carbohydrate arrays (glycoarrays) have recently emerged as a high-throughput tool for studying carbohydrate-binding proteins and carbohydrate-processing enzymes. A number of sophisticated array platforms that allow for qualitative and quantitative analysis of carbohydrate binding and modification on the array surface have been developed, including analysis by fluorescence spectroscopy, mass spectrometry and surface plasmon resonance spectroscopy. These platforms, together with examples of biologically-relevant applications are reviewed in this Feature Article.
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