Cucurbituril-based nanoparticles: a new efficient vehicle for targeted intracellular delivery of hydrophobic drugs
Chemical Communications2008Iss. 1, pp. 71–73
Citations Over TimeTop 10% of 2008 papers
Kyeng Min Park, Kyungwon Suh, Hyuntae Jung, Don‐Wook Lee, Youngjoo Ahn, Jeeyeon Kim, Kangkyun Baek, Kimoon Kim
Abstract
Cucurbituril-based nanoparticles (CB[6]NPs) serve as new efficient vehicles for delivery of hydrophobic drugs, which have unique features including (1) a high drug loading capacity and efficiency, (2) noncovalently tunable surfaces, (3) efficient delivery of hydrophobic drugs into a cancer cell by receptor-mediated endocytosis, and (4) facile release of drugs into cytoplasm, which enhances the pharmaceutical effects of the drugs.
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