Mesoporous silica nanoparticles functionalized with an oxygen-sensing probe for cell photodynamic therapy: potential cancer theranostics

Citations Over TimeTop 1% of 2009 papers

Abstract

Functionalization of mesoporous silica nanoparticles (MSNs) with Pd-porphyrins for cancer cell photodynamic therapy is reported. The composite platform, MSN–PdTPP, expands the role of Pd-porphyrins from their routine use as phosphorescence probes for oxygen sensing/imaging (diagnostics) to that of novel nano-photosensitizers for cancer cell phototherapy (therapeutics). The utility of MSN–PdTPP in the phototherapeutic treatment of MDA-MB-231 breast cancer cells is also evaluated, suggesting it is a promising cancer theranostic platform.

Related Papers

• → Aggregation induced phosphorescence of metal complexes: From principles to applications(2017)208 cited
• → Achieving Colorful Ultralong Organic Room-Temperature Phosphorescence by Precise Modification of Nitrogen Atoms on Phosphorescence Units(2023)34 cited
• → On the nature of tyrosine phosphorescence from proteins(1966)19 cited
• → The phosphorescent state of the 1,2,4,5-tetracyanobenzene-naphthalene complex(1975)17 cited
• → [11] Application of phosphorescence to the study of proteins(1978)7 cited