Targeting glycolysis: a fragment based approach towards bifunctional inhibitors of hLDH-5
Chemical Communications2010Vol. 47(1), pp. 230–232
Citations Over TimeTop 22% of 2010 papers
Abstract
hLDH-5 has emerged as a promising target for anti-glycolytic cancer chemotherapy. Here we report a first generation of bifunctional inhibitors, which show promising activity against hLDH-5.
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