Coercing bisphosphonates to kill cancer cells with nanoscale coordination polymers
Chemical Communications2012Vol. 48(21), pp. 2668–2668
Citations Over TimeTop 10% of 2012 papers
Demin Liu, Stephanie Krämer, Rachel C. Huxford‐Phillips, Shunzhi Wang, Joseph Della Rocca, Wenbin Lin
Abstract
Nanoscale coordination polymers containing exceptionally high loadings of bisphosphonates were coated with single lipid bilayers to control the drug release kinetics and functionalized with a targeting ligand to endow cell-targeting capability, leading to much enhanced cytotoxicity against human lung and pancreatic cancer cells.
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