Immobilization of engineered arginase on gold-carbon nanotubes
Chemical Communications2012Vol. 48(62), pp. 7693–7693
Citations Over TimeTop 25% of 2012 papers
Gordon Kuen-Chan Lee, Sui-Yi Kwok, Chih Hao Yu, Kin Yip Tam, Hiu‐Chi Chong, Yun‐Chung Leung, Shik Chi Edman Tsang
Abstract
It is demonstrated that engineered arginase with a single protruded site of cysteine deliberately placed away from its active centre by site-directed mutagenesis can facilitate its attachment on a gold-nanoparticle surface with atomic precision, resulting in no apparent loss in enzymatic activity.
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