Simultaneously sensitive detection of multiple miRNAs based on a strand displacement amplification
Chemical Communications2012Vol. 49(1), pp. 75–77
Citations Over TimeTop 10% of 2012 papers
Tian Tian, Heng Xiao, Xiao‐Lian Zhang, Shuang Peng, Xiaoe Zhang, Shan Guo, Shaoru Wang, Song‐Mei Liu, Xin Zhou, Xin Zhou, Craig Meyers, Xiang Zhou, Xiang Zhou
Abstract
We reported an efficient strategy based on a strand displacement amplification for serum miRNA detection. In such a system, a multiplexed, sensitive and quick detection of miRNAs could be achieved through a combination of fluorescence labeled probes, a common primer and a polymerase. This could be potentially used in the clinical field to achieve early disease diagnosis and prognosis.
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