A selective fluorescent turn-on NIR probe for cysteine
Organic & Biomolecular Chemistry2012Vol. 10(10), pp. 1966–1966
Citations Over TimeTop 10% of 2012 papers
Abstract
A selective and sensitive turn-on fluorescent NIR probe for cysteine has been developed. Cleavage of 2,4-dinitrobenzenesulfonyl (DNBS) with thiols switches the weakly fluorescent aza-BODIPY dye (λ(em) = 734 nm, Φ(f) = 0.03) to a strongly fluorescent species in the NIR region (λ(em) = 755 nm, Φ(f) = 0.14).
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