Highly specific triple-fragment aptamer for optical detection of cocaine
RSC Advances2012Vol. 2(11), pp. 4636–4636
Citations Over TimeTop 19% of 2012 papers
Ruxing Zou, Xinhui Lou, Huichao Ou, Ying Zhang, Wenjie Wang, Min Yuan, Ming Guan, Zhaofeng Luo, Yueying Liu
Abstract
For the first time an anti-cocaine aptamer was cut into three fragments, which were still able to specifically assemble with cocaine and render the sensitive and highly selective optical detection of cocaine. The assembly process possesses significantly different thermodynamic signature compared to the interactions involved monolithic aptamer and double-fragment aptamer.
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